Back to Ask the Diabetes Team Ask the Diabetes Team

From Roswell, Georgia, USA:

Is it safe to take the newly released Xenadrine RFA (ephedrine free) if you have type 2 diabetes and are taking Glucophage [metformin]?


I believe that Xenadrine RFA-1 contains ephedra which has the following warnings:

Contraindications include increased blood pressure, increased heart rate, heart palpitations, and can lead to stroke. Do not take ephedra if you are pregnant, nursing or have heart disease, anxiety disorders (panic attacks), high blood pressure, diabetes, glaucoma, or an overactive thyroid gland (hyperthyroidism).
I would not feel comfortable recommending this product for someone with diabetes. I suggest you consider safer methods of weight loss such as working with a registered dietician and/or joining Weight Watchers or some other sensible weight loss program.


[Editor's comment: The manufacturers website says the following about this product:

  • Capsules per bottle: 120
  • Servings per bottle: 60 (30 day cycle)
  • Two capsules of Xenadrine contain:
  • Citrus Aurantium (4% synephrine): 125 mg
  • MaHuang (6% ephedrine): 335 mg
  • Guarana Extract (22% caffeine) 910 mg
  • White Willow Bark (15% salicin): 105 mg
  • Acetyl L-Carnitine: 100 mg
  • L-Tyrosine: 80 mg
  • Ginger Root: 50 mg
  • Vitamin B5: 40 mg
  • Ingredients: Calcium Phosphate, Talc, Gelatine, Magnesium Stearate.

[Editor's comment: Looking around the Internet, it appears that Xenadrine RFA does indeed contain ephedra, contrary to your understanding. Ephedra is the herb that contains ephedrine. It is also known as Ma Huang and has been used in China for medicinal purposes for thousands of years. Ephedrine is metabolized to norephedrine, which is responsible for the nervous system stimulating effects of the drug. WWQ]

Original posting 3 Dec 2002
Posted to Other Medications


  Back to Ask the Diabetes Team Return to the Top of This Page

Last Updated: (none)
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2018. Comments and Feedback.