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From Longmont, Colorado, USA:

If you had no previous history of diabetes, then the chances of the offspring inheriting diabetes are close to nil or never. The genetic code won't be affected if you acquired diabetes without inheriting it. Is this true?


Not quite. However, type 1 diabetes is less likely to occur along familial lines than type 2 diabetes. More people with type 1 diabetes do not have a family history of the condition, although some do. Type 2 diabetes is associated with approximately a 50% chance of occurring in offspring of people with type 2 diabetes. With type 1 diabetes, there is a stronger risk of passing on type 1 diabetes if the father has type 1 diabetes, compared to the mother having the condition. Finally, we think there may be an inherited predisposition to the immune response which occurs and causes type 1 diabetes. The genetics of type 1 diabetes is not yet worked out to provide a definitive mechanism for families in which it occurs.


Original posting 30 May 2001
Posted to Genetics and Heredity


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