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From McCleary, Washington, USA:

I recently got put on NPH and Regular insulin shots twice a day, because my doctor is trying to see if taking insulin will possibly prevent type 2 diabetes in me. Is this possible?


I know of no research into prevention of type 2 diabetes by giving insulin. I do know that there is a project of the NIH, the Diabetes Prevention Trial for Type 1 or DPT-1 trial, in which insulin is the specific intervention.

For type 2, the Diabetes Prevention Program (at the Diabetes Monitor). intervenes with diet, exercise, and, for some, the drug Glucophage [metformin]. So, I can't answer the first question based on any research. I have given the research as I know it. You might ask whether your doctor is thinking of type 1 or type 2. If your doctor is thinking of type 1, has he looked at islet cell antibodies, etc? These are increased in those predisposed to type 1 diabetes a lot of the time. For type 2, has he looked at C-peptide, a measure of insulin secretion? That might be helpful.


Original posting 23 Apr 2001
Posted to Research: Causes and Prevention


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