From Nebraska, USA:
There has been much in the news lately about increasing number of cases of Type 2 in children. These articles only mention obesity and/or non-Caucasians. Is there any information on nonobese, Caucasian children with Type 2? My daughter, 14, is one such case. Her diabetes was discovered at a routine sports physical (urinalysis) which was followed by a glucose tolerance test two years ago. It was assumed that she was early Type 1 as she is not overweight and is Caucasian. But her condition has not worsened in all these months, plus certain genetic tests (HLA typing) indicate she does not have the "DQ" type that 95% of Type 1's have. She also tested negative on all the autoantibodies usually seen in Type 1.
Most of the Type 2 diabetes in children and teens is clearly related to obesity and high risk groups. Suffice it to say there are other possibilities.
The other possibilities involves insulin resistance. Ask her doctor to measure a C-peptide; it should be high. Likewise if she isn't on insulin, her insulin level might be high.
There is also an insulin resistant hirsutism (excess hair) and elevated androgen syndrome. Likewise there is the syndrome of acanthosis nigricans. Any pediatric endocrinologist should be familiar with these concepts, and help you ascertain if they might apply to your daughter's case.
Original posting 4 Feb 1999
Posted to Diagnosis and Symptoms
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