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From California, USA:

They recently checked my daughter's cord blood at birth for islet cell antibodies. This test was positive. They checked my wife for ISA's to see if they were passed in the womb, but my wife's test was negative. I do have a son who is 15, and has had type 1 diabetes for 5 years. My question is how many newborns are testing positive for ISA's, and what does this positive test mean as far as my daughter getting IDDM?


I do not know the answer to your question so I talked to Dr. Li Ping, who runs Dr. Eisenbarth's antibody lab [at the Barbara Davis Center in Colorado]. For what it is worth he told me that he had never come across a positive antibody test in a newborn that was not due to passively transferred antibodies from the mother. In the circumstances, I would wait six months and repeat the test in the baby.


Original posting 27 Mar 1998
Posted to Research: Causes and Prevention


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