Back to Diabetes Basics PHHI

Persistent Hyperinsulinaemic Hypoglycaemia of Infancy (PHHI), also known as nesidioblastosis, is a rare, usually inherited condition in which the pancreas produces too much insulin. This is the exact opposite of what happens in type 1 diabetes, but care involves frequent blood sugar tests as with kids with diabetes.

Babies born with PHHI can have severely low blood sugar levels and seizures, and are at high risk for brain damage if blood sugar levels are not maintained at sufficiently high levels. Treatment can include medications, additional feedings, and even removal of up to 90-95% of the pancreas.


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